In the spotlight
Astellas and University of Pittsburgh Announce Research Collaboration for Treatment of Dry Age-related Macular Degeneration
In this collaboration, Debasish Sinha, Ph. D., Jennifer Salvitti Davis, M.D. Chair in Ophthalmology Research and Professor of Ophthalmology, Cell Biology and Developmental Biology in University of Pittsburgh School of Medicine, a world-renowned authority in the research field of back-of-the-eye diseases, and Astellas, who has capabilities in drug discovery, will work jointly to evaluate and optimize the drug candidates with an aim to provide new treatment options that help recover and maintain vision for the patients suffering from dry AMD.
"Age-related Macular Degeneration (AMD)"
Sight + Sound Bites Webinar series.
This webinar, featuring José-Alain Sahel, MD, Thomas Friberg, MD, FACS, Joseph Martel, MD, and Debasish Sinha, PhD, explores the causes and treatments of AMD (Recorded July 7, 2020).
"Understanding The Underlying Molecular Basis"
Advanced Retina Clinix Live Webinar.
Dr. Debasish Sinha's talk starts at 1h 29 min (Recorded May 30, 2020).
This new finding may help in developing treatment for age-related macular degeneration
"A team of scientists has unraveled the molecular mechanism behind the development of age-related macular degeneration (AMD). It has found that it develops because of abnormal activity of a set of white blood cells called neutrophils and that it can be stopped, and even reversed, by targeting it.
Building the Best Team for Macular Degeneration
In December of 2016, Dr. E. Ronald Salvatti extended his commitment to the Department of Ophthalmology at the University of Pittsburgh by endowing the Jennifer Salvatti Davis, MD Chair in Ophthalmology Research, to honor his daughter, an Ophthalmologist and a member of his practice. Debasish Sinha, PhD was awarded this chair when he was appointed to the Department.
Primary cell cultures from the mouse retinal pigment epithelium
The video protocol has been published in JoVE
Nobel Prize Discoveries Pave Way for Curing Mind and Sight Diseases
BrightFocus Grantee Connects with Laureate’s ‘Disciples’
"It’s amazing work, and something that may affect many diseases,” BrightFocus grantee Debasish Sinha, PhD, of Johns Hopkins Wilmer Eye Institute, said of Ohsumi’s foundational work to explain autophagy.
Sinha is using a new 2016-18 grant from BrightFocus’ Macular Degeneration Research (MDR) program, as well as a recently completed 2014-16 grant, to study the role of autophagy in age-related macular degeneration (AMD)."