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In the spotlight

Dr. Sayan Ghosh is featured in the recent PittWire newsletter for receiving a highly competitive fellowship for AMD Research

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Ophthalmology’s Sayan Ghosh has been awarded a postdoctoral fellowship from the BrightFocus Foundation for his research on understanding the role of inflammation in age-related macular degeneration (AMD). BrightFocus funds research into Alzheimer’s disease, macular degeneration and glaucoma.

Ghosh, a postdoctoral associate who works in Debasish Sinha’s lab, has published numerous papers on AMD, working to unravel the molecular mechanisms associated with inflammation and the disease.

Astellas and University of Pittsburgh Announce Research Collaboration for Treatment of Dry Age-related Macular Degeneration


In this collaboration, Debasish Sinha, Ph. D., Jennifer Salvitti Davis, M.D. Chair in Ophthalmology Research and Professor of Ophthalmology, Cell Biology and Developmental Biology in University of Pittsburgh School of Medicine, a world-renowned authority in the research field of back-of-the-eye diseases, and Astellas, who has capabilities in drug discovery, will work jointly to evaluate and optimize the drug candidates with an aim to provide new treatment options that help recover and maintain vision for the patients suffering from dry AMD. 

"Age-related Macular Degeneration (AMD)"

Sight + Sound Bites Webinar series. 

This webinar, featuring José-Alain Sahel, MD, Thomas Friberg, MD, FACS, Joseph Martel, MD, and Debasish Sinha, PhD, explores the causes and treatments of AMD (Recorded July 7, 2020).

"Understanding The Underlying Molecular Basis"

Advanced Retina Clinix Live Webinar.

Dr. Debasish Sinha's talk starts at 1h 29 min (Recorded May 30, 2020).

This new finding may help in developing treatment for age-related macular degeneration


"A team of scientists has unraveled the molecular mechanism behind the development of age-related macular degeneration (AMD). It has found that it develops because of abnormal activity of a set of white blood cells called neutrophils and that it can be stopped, and even reversed, by targeting it.

Building the Best Team for Macular Degeneration


In December of 2016, Dr. E. Ronald Salvatti extended his commitment to the Department of Ophthalmology at the University of Pittsburgh by endowing the Jennifer Salvatti Davis, MD Chair in Ophthalmology Research, to honor his daughter, an Ophthalmologist and a member of his practice. Debasish Sinha, PhD was awarded this chair when he was appointed to the Department.

Primary cell cultures from the mouse retinal pigment epithelium

The video protocol has been published in JoVE

Nobel Prize Discoveries Pave Way for Curing Mind and Sight Diseases

BrightFocus Grantee Connects with Laureate’s ‘Disciples’


"It’s amazing work, and something that may affect many diseases,” BrightFocus grantee Debasish Sinha, PhD, of Johns Hopkins Wilmer Eye Institute, said of Ohsumi’s foundational work to explain autophagy.

Sinha is using a new 2016-18 grant from BrightFocus’ Macular Degeneration Research (MDR) program, as well as a recently completed 2014-16 grant, to study the role of autophagy in age-related macular degeneration (AMD)."

"Age-related Macular Degeneration (AMD):

The Patients' View"

presented by Dr. Debasish Sinha (recorded March 9, 2018)

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